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etravirine will lower the extent or effect of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of abemaciclib with robust CYP3A4 inducers cuts down plasma concentration of abemaciclib and its metabolites.dabrafenib will minimize the level or result of abemaciclib by influenc